Pengamatan Jangka Panjang dan Intervensi Anak dengan Rakhitis dan Hipovitaminosis D
Abstract
Rickets is associated with impaired calcium and phosphate homeostasis, which can lead to short stature and joint deformities. Nutritional rickets results from deficiencies of vitamin D, calcium and phosphate. Vitamin D regulates calcium and phosphorus in the blood, if there is a deficiency of vitamin D it results in inadequate mineralization of osteoid produced by osteoblasts. It is important to ensure adequate vitamin D supplementation in nutritional rickets and rule out vitamin D deficiency in other forms of rickets, which may hinder healing of rickets. Medical rehabilitation can improve functional independence by reducing pain and improving joint mobility, muscle strength, endurance, and gait in rickets patients.
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Chanchlani R, Nemer P, Sinha R, Nemer L, Krishnappa V, Sochett E, et al. An Overview of Rickets in Children. Vol. 5, Kidney International Reports. Elsevier Inc; 2020. p. 980–90.
Carpenter TO, Shaw NJ, Portale AA, Ward LM, Abrams SA, Pettifor JM. Rickets. Nat Rev Dis Primers. 2017 Dec 21;3.
Haffner D, Leifheit-Nestler M, Grund A, Schnabel D. Rickets guidance: part II—management. Pediatric Nephrology. 2022 Oct 1;37(10):2289–302.
Palkrit S, Chitale N, Phansopkar P, Deshmukh M. Physiotherapy Management of an Adolescent With Pityriasis Rubra Pilaris Along With Rickets. Cureus. 2022 Oct 20;
Haffner D, Leifheit-Nestler M, Grund A, Schnabel D. Rickets guidance: part I—diagnostic workup. Vol. 37, Pediatric Nephrology. Springer Science and Business Media Deutschland GmbH; 2022. p. 2013–36.
Gentile C, Chiarelli F. Rickets in Children: An Update. Biomedicines. 2021 Jun 27;9(7):738.
Dahash BA, Sankararaman S. Rickets. StatPearls [Internet] Treasure Island (FL): StatPearls. 2023;Januari.
WHO. Nutritional Rickets: A review of disease burden, causes, diagnosis, prevention and treatment. 2019 [cited 2023 Nov 20]; Available from: https://www.who.int/publications/i/item/9789241516587
Pulungan A, Soesanti F, Tridjaja B, Batubara J. Vitamin D insufficiency and its contributing factors in primary school-aged children in Indonesia, a sun-rich country. Ann Pediatr Endocrinol Metab. 2021;26(2):92–8.
Özkan B. Nutritional rickets. JCRPE Journal of Clinical Research in Pediatric Endocrinology. 2010 Dec;2(4):137–43.
Uday S, Högler W. Nutritional rickets & osteomalacia: A practical approach to management. Vol. 152, Indian Journal of Medical Research. Wolters Kluwer Medknow Publications; 2020. p. 356–67.
Charoenngam N. Vitamin d and rheumatic diseases: A review of clinical evidence. Vol. 22, International Journal of Molecular Sciences. MDPI; 2021.
Ismunandar H, Himayani R, Al Farisi M. Rakhitis: Tinjauan Pustaka. Vol. 10, Tinjauan Pustaka Medula |.
Pradhan R, Agarwal A, Gupta SK. PHPT masquerading as rickets in children and presenting with rare skeletal manifestations: Report of three cases and review of literature. Indian J Endocrinol Metab. 2018 Sep 1;22(5):705–9.
Chang CY, Rosenthal DI, Mitchell DM, Handa A, Kattapuram S V., Huang AJ. Imaging findings of metabolic bone disease. Radiographics. 2016 Oct 1;36(6):1871–87.
Thacher TD, Pettifor JM, Tebben PJ, Creo AL, Skrinar A, Mao M, et al. Rickets severity predicts clinical outcomes in children with X-linked hypophosphatemia: Utility of the radiographic Rickets Severity Score. Bone. 2019 May 1;122:76–81.
Thacher TD. Calcium-deficiency rickets. Vol. 6, Endocrine development. 2003. p. 105–25.
Lee JY, So TY, Thackray J. • www.jppt.org INDEX TERMS cholecalciferol, ergocalciferol, pediatric, vitamin D deficiency [Internet]. Vol. 18, J Pediatr Pharmacol Ther. 2013. Available from: www.jppt.org
Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: An endocrine society clinical practice guideline. Vol. 96, Journal of Clinical Endocrinology and Metabolism. 2011. p. 1911–30.
Abousamra O. Reconstructive Considerations in Rickets: Medical Optimization, Growth Modulation, and Osteotomies. Oper Tech Orthop. 2021 Jun 1;31(2).
