Differences in Levels of 25-hydroxyvitamin D, Human Chorionic Gonadotropin (hCG), and Progesterone in Normal Pregnancy and First Trimester Abortion

Abstract

Early pregnancy failure was defined as the failure of an intrauterine pregnancy less than 12 weeks old.

This research is a comparative analytic study with  a  cross   sectional    approach. the sampling technique was consecutively taken. The normality of data was tested with the Saphiro Wilk test and data analysis with the Independent T test.

Vitamin D levels were significantly higher in normal pregnancies than in the abortion group, in line with vitamin D levels as well as hCG levels and progesterone levels were significantly higher in normal pregnancies than in the abortion group. This explains the theory that vitamin D in trophoblast plays a role in regulating the production of hCG and progesterone.

The conclusion in this study was that the average level of 25-hydroxyvitamin D, Human Chorionic Gonadotropin(hCG), and Progesterone were significantly different between normal pregnancies and pregnancies that had abortions in the first trimester.