Omega-3 for Inflammatory Bowel Disease: Is it worthy?- A Literature Review
Abstract
Tujuan: Memberikan pemahaman mengenai potensi terapeutik asam lemak omega-3 dalam penanganan Inflammatory Bowel Disease (IBD). Metode: Artikel ini disusun berdasarkan metode tinjauan literatur. Sumber data diperoleh dari artikel-artikel ilmiah yang dipublikasikan di jurnal internasional berbahasa Inggris. Proses pencarian literatur dilakukan melalui mesin pencari Google Scholar dan PubMed. Hasil: Inflammatory Bowel Disease (IBD), yang mencakup kondisi seperti Ulcerative Colitis (UC) dan Crohn's Disease (CD), merupakan kelompok gangguan inflamasi kronis yang mempengaruhi saluran pencernaan. Dalam beberapa tahun terakhir, asam lemak omega-3 telah menjadi titik perhatian dalam diskusi IBD, terutama karena sifat anti-inflamasinya. Penelitian epidemiologi menunjukkan bahwa diet kaya omega-3 dapat meningkatkan kemungkinan remisi klinis pada pasien IBD. Sebagai contoh, pasien UC yang mengonsumsi salmon Alaskan dalam jumlah tinggi menunjukkan penurunan marker inflamasi dibandingkan dengan kelompok kontrol. Kesimpulan: Bukti saat ini menunjukkan bahwa makanan alami yang kaya omega-3, seperti salmon, memiliki potensi manfaat dalam penanganan Inflammatory Bowel Disease.
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