Korelasi plak, CIMT, dan skor kalsium dengan derajat stenosis arteri koroner pada pasien dislipidemia

Erman Muliawan✉, Nikmatia Latief, Sri Asriyani, Andi Alfian Zainuddin, Muzakkir Amir, Mirna Muis
DOI: https://doi.org/10.25077/mka.v42.i3S.p1-10.2019

Abstract

Tujuan: Mengetahui korelasi plak, ketebalan tunika intima-media arteri karotis berdasarkan ultrasonografi dan skor kalsium total dengan derajat stenosis arteri koroner berdasarkan MSCT-scan kardiak pada pasien dislipidemia. Metode: Cross-sectional, dilakukan di instalasi radiologi sentral RSUP dr. Wahidin Sudirohusodo, Makassar mulai bulan Juli 2018 sampai Juli 2019. Sampel sebanyak 32 orang dengan usia >18 tahun dan memiliki riwayat dislipidemia. Metode statistik yang digunakan uji korelasi Spearman. Hasil: Terdapat korelasi antara kejadian plak, ketebalan tunika intima-media arteri karotis dan total calcium score dengan derajat stenosis arteri koroner, dimana nilai p masing-masing secara berurutan yaitu 0,017 (<0,05), <0,0001, dan <0,0001 dan nilai r masing-masing yaitu 0,418, 0,65, dan 0,882. Simpulan: Skor kalsium total merupakan suatu penanda independen risiko kejadian kardiovaskular, lebih superior dibandingkan evaluasi arteri karotis. Terdapatnya nilai skor kalsium total menunjukkan adanya suatu penyakit arteri koroner namun tidak memprediksi obstruksi luminal. Di samping itu, keadaan dinding arteri karotis juga dapat mencerminkan keadaan dinding arteri koroner sehingga dapat digunakan sebagai penanda terjadinya aterosklerosis pada pembuluh darah jantung pada daerah yang belum memiliki fasilitas skor kalsium total.

Keywords

dislipidemia; plak arteri karotis; ketebalan tunika intima-media arteri karotis; total calcium score; derajat stenosis arteri koroner

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