The potency of secondary metabolites from traditional medicine plants as anti cancer agent

Abstract

The seconday metabolites from traditional medicine plants have played an important role in
cancer treatment. Exploration of natural active compounds from medicinal plants for cancer
treatment has attracted substantial attention worldwide. Several secondary metabolites that
were isolated fom the plants, such as vincristne, vinblastine, campthothecins, have been used
have been used clinically for over 40 years. Numerous techniques have been developed
to obtain compounds for drug discovery including isolation from plants, synthetic chemistry,
screening bioassays. As part of efforts to discover phytochemicals as anticancer agent, our
group were isolated several compunds mainly from Annonaceae and Melliaceae family that
showed active againts human leukemia HL-60 cells.