Analisis Motilitas Dan Morfologi Spermatozoa Pria perokok Usia 18-24 tahun

yosha putri wahyuni


Background: Smoking is one of lifestyle factors which lead to health problems in society. Smoke can decrease the quality of spermatozoa by various mechanisms, one of which is the seminal oxidative stress induced by Reactive Oxygen Species (ROS). Excessive levels of ROS lead to the lipid peroxidation and the changes in sperm membrane function resulting to the decreased of sperm morphology, sperm motility and fertility.

Objective: The purpose of this research is to determine the effect of smoking activity to sperm motility and morphology in men adult at the age between 18 and 24.

Methods: This research was analytic research conducted using a cross sectional design. This study selected 52 males using a purposive random sampling technique. The examination of sperm motility and morphology was conducted using a microscope by counting 100 sperms.

Results: The result showed that there was a difference of sperm    motility between men who are smokers and non-smokers (p<0,05). However, there were not a significance difference of sperm morphology between men smokers and non-smokers at p>0,05.

Conclusion: The research concluded that a smoking activity can influence men sperm motility but not the morphology of the samples of this study. 


Motility; Morphology; Smoking; Sperm

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Agarwal, A., Mulgund, A., Alshahrani, S., Assidi, M., Abuzenadah, A. M., Sharma, R., & Sabanegh, E. Reactive oxygen species and sperm DNA damage in infertile men presenting with low level leukocytospermia. Reproductive biology and endocrinology. 2014; 12(1), 1-8.

Ansari, Shamshad. A Prospective Study on Effect of Cigarette Smoking on Male Fertility in a Tertiary Care Hospital‟, International J of Medical Research Professionals, vol. 2, no. 1, Januari 2016; hlm. 57—60, diakses 4 Desember 2016,

Apriora VD, Amir A, Khairsyaf O. Gambaran Morfologi Spermatozoa pada Perokok Sedang di Lingkungan PE Group yang Datang ke Bagian Biologi Fakultas Kedokteran Universitas Andalas. Jurnal Kesehatan Andalas. 2015 May 1;4(2).

Asare-Anane, H., Bannison, S. B., Ofori, E. K., Ateko, R. O., Bawah, A. T., Amanquah, S. D & Ziem, J. B. Tobacco smoking is associated with decreased semen quality. Reproductive Health. 2016; 13(1), 1-6.

Eskenazi B, Wyrobek AJ, Sloter E, Kidd SA, Moore L, Young S, Moore D. The association of age and semen quality in healthy men. Human reproduction. 2003 Feb 1;18(2):447-54.

Ghaffari, MA, Rostami, M. The Effect of Cigarette Smoking on

Health Service Executive 2014, Smoking in Ireland: Synopsis of Key Pattern, HSE National Tobacco Control, diakses 24 Agustus 2016.

Guyton, A. C., & Hall, J. E. 2007. Buku ajar fisiologi kedokteran. EGC.

Jungwirth A, Diemer T, Dohle GR, Giwercman A, Kopa Z, Krausz C, Tournaye H. Guidelines on male infertility: European Association of Urology. EAU Guidelines Office. 2013.

Nadeem, F, Fahim, A, Bugti, S. Effects of cigarette smoking on male fertility‟, Turk J Med Sci, , vol. 42, no. 2, Juni 2012, hlm. 1400—1405, diakses 22 Agustus 2016,

Pasqualotto FF, Sobreiro BP, Hallak J, Pasqualotto EB, Lucon AM. Sperm concentration and normal sperm morphology decrease and follicle-stimulating hormone level increases with age. BJU international. 2005 Nov 1;96(7):1087.

Sankako MK, Garcia PC, Piffer RC, Pereira OC. Semen and reproductive parameters during some abstinence periods after cigarette smoke exposure in male rats. Brazilian Archives of Biology and Technology. 2013 Feb;56(1):93-100.

Sharma R, Agarwal A, Rohra VK, Assidi M, Abu-Elmagd M, Turki RF. Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring. Reproductive Biology and Endocrinology. 2015 Dec;13(1):1-20.

Sunanda P, Panda B, Dash C, Padhy RN, Routray P. Effect of age and abstinence on semen quality: A retrospective study in a teaching hospital. Asian Pacific Journal of Reproduction. 2014 Jun 1;3(2):134-41.