Hubungan pemeriksaan LED dan CRP pada penegakkan diagnosis Spondilitis Tb di RSUP dr. M. Djamil Padang tahun 2014-2016

Bayu Fajar Wibowo✉, Menkher Manjas, Roni Eka Sahputra, Erkadius Erkadius
DOI: https://doi.org/10.25077/mka.v41.i2.p69-77.2018

Abstract

Spondilitis Tuberkulosis (Tb) merupakan manifestasi Tb tulang yang paling berbahaya dan paling sering ditemukan. Perubahan nilai hematologi berupa pengukuran nilai Laju Endap Darah (LED) dan C-Reactive Protein (CRP) digunakan dalam penegakkan diagnosa, penilaian prognosis dan efektivitas pengobatan Spondilitis Tb. Tujuan: Untuk mengetahui hubungan dan akurasi diagnostik LED dan CRP pada pasien spondilitis Tb. Metode: Penelitian ini menggunakan desain retrospective cohort study pada 53 penderita diduga Spondilitis Tb yang belum pernah mendapatkan terapi OAT, tetapi telah menjalani operasi dan pemeriksaan histopatologi pada periode Januari 2014 hingga Desember 2016, di RSUP dr. M. Djamil Padang dan diolah dengan analisis Fisher’s Exact Test. Hasil: Tidak terdapat hubungan yang bermakna antara kejadian Spondilitis Tb dan nilai LED dengan p-value 0,280 (p>0,05). Tidak terdapat hubungan yang  bermakna antara kejadian Spondilitis Tb dengan nilai kualitatif CRP dengan p-value 0,886 (p>0,05). Simpulan: Berdasarkan hasil tersebut, dapat disimpulkan bahwa pemeriksaan LED dan CRP tidak spesifik untuk diagnosis Spondilitis Tb, kecuali CRP memiliki sensitivitas yang tinggi.

Keywords

Sponditilis Tb; LED; CRP; diagnostik

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