Breakhthrough Infection Pasca Pemberian Booster mRNA Heterolog pada Tenaga Kesehatan di RSUD Arifin Achmad

Dina Br Nababan✉, Eka Bebasari, Ligat Pribadi Sembiring, Dani Rosdiana, Rahmat Azhari Kemal
DOI: https://doi.org/10.25077/mka.v46.i2.p343-347.2023

Abstract

Tujuan: Mengetahui prevalensi dan karakteristik responden breakthrough infection pada tenaga kesehatan di RSUD Arifin Achmad Provinsi Riau dalam 14 hari – 6 bulan pasca vaksinasi booster mRNA-1273. Metode: Metode penelitian cross sectional yang dilakukan pada Juli – September 2022 menggunakan sampel sebanyak 123 responden melalui wawancara. Hasil: 14 responden (11,4%) mengalami breakthrough infection. Mayoritas responden breakthrough infection berjenis kelamin perempuan (78,6%), rata-rata usia 44,1 tahun, pekerjaan dokter (42,9%), IMT obesitas (57,1%), mayoritas tidak ada komorbid (85,7%) dan bukan penyintas (85,7%). Simpulan: Terdapat kejadian breakthrough infection pada tenaga kesehatan di RSUD Arifin Ahmad pada 14 hari – 6 bulan pasca pemberian booster mRNA Heterolog (mRNA-1273).

Kata kunci: breakthrough infection; vaksin booster; mRNA-1273; vaksin heterolog; COVID-19

Keywords

breakthrough infection; vaksin booster; mRNA-1273; vaksin heterolog; COVID-19

Full Text:

PDF

References

Khoirunisa NA, Wiraguna JA, Naully PG. An Overview Of The Immunity Of Health Workers After Covid-19 Vaccinations. In: 4th International Seminar On Global Helath. 2021. p. 58–63.

Kementerian Kesehatan RI. Surat Edaran Nomor : Hk.02.02/Ii/252/2022 Tentang Vaksinasi Covid-19 Dosis Lanjutan (Booster). Kementerian Kesehatan RI. Jakarta; 2022. p.1–25.

Jain S, Batra H, Yadav P, Chand S. Covid-19 Vaccines Currently Under Preclinical And Clinical Studies, And Associated Antiviral Immune Response. Vaccines. 2020;8(4):1–16.

Naaber P, Tserel L, Kangro K, Sepp E, Jürjenson V, Adamson A, Et Al. Dynamics Of Antibody Response To BNT162b2 Vaccine After Six Months: A Longitudinal Prospective Study. Lancet Reg Heal Eur. 2021;10:3–8.

Birhane M, Bressler S, Chang G, Clark T, Dorough L, Fischer M, Et Al. Covid-19 Vaccine Breakthrough Infections Reported To Cdc — United States, January 1–April 30, 2021. Vol. 70, Mmwr. Morbidity And Mortality Weekly Report. Centers For Disease Control Mmwr Office; 2021.

Asnajaya D. Peningkatan Titer Imunoglobulin G Dan Kejadian Covid-19 Pasca Vaksinasi Covid-19 Pada Tenaga Kesehatan Tanpa Riwayat Covid-19. Universitas Sebelas Maret; 2022.

Basso P, Negro C, Cegolon L, Filon FI. Risk Of Vaccine Breakthrough Sars-Cov-2 Infection And Associated Factors In Healthcare Workers Of Trieste Teaching Hospitals (North-Eastern Italy). Viruses. 2022;14:1–12.

Bergwerk M, Gonen T, Lustig Y, Amit S, Lipsitch M, Cohen C, Et Al. Covid-19 Breakthrough Infections In Vaccinated Health Care Workers. N Engl J Med. 2021;385(16):1474–84.

Hasanah U, Ramdani D, Darmawan E, Sugiyarto S. Hubungan Indeks Massa Tubuh Dengan Keparahan Dan Mortalitas Pasien Covid-19. J Kesehat. 2022;13(2):272.

Nelwan RM, Doda DVD, Mongan AE. Faktor Individu Dan Pekerjaan Yang Berhubungan Dengan Kejadian Infeksi Corona Virus Disease ( Covid-19 ) Pada Pekerja Di Rsup Ratatotok Buyat. E-Clinic. 2022;11(1):40–50.

Mariani A, Kurniawidjaja M. Analisis Faktor Risiko Covid-19 Pada Pekerja Perkantoran Dinas Kesehatan Provinsi DKI Jakarta. Prepotif J Kesehat Masy. 2022;6(2):1218–32.



Bookmark and Share
-->