Preliminary Screening of Phytochemical Compounds of Jeriangau (Acorus calamus) from West Sumatra
Abstract
Indonesia's biodiversity is able to meet the needs of human life in various sectors, especially in the utilization of potential plants. Jeriangau (Acorus calamus) is a rhizome plant that is widely used as traditional medicine in various ethnicities, especially in West Sumatra. This is because jeriangau contains bioactive compounds that have the potential to treat various diseases. This research method is an experimental study to qualitatively confirm the bioactive components contained in the rhizome of Jeriangau. The test results of jeriangau simplicia samples showed positive results for the active group of secondary metabolites of flavonoids, tannins, and saponins which have potential as antioxidants. Flavonoids can reduce the risk of chronic disease, especially cardiovascular disease and cancer. Tannins have antioxidant properties and can protect the skin from damage caused by UV radiation. Saponins are known to act as antiviral, antimicrobial, and anti-inflammatory. Therefore, Acorus calamus extract can be used as an antibacterial, antiviral, antiseptic, antifungal, and acts as an antioxidant. Further research is needed on studies of inflammatory activity, either in vitro, in vivo, or in human treatment.
Keywords: jeriangau; phytochemicals; West Sumatra; antioxidant.
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Tobing IS, Sukara E. Industri Berbasis Keanekaragaman Hayati, Masa Depan Indonesia. Vis Vitalis 2008;01(2):1–12.
Suhartini. Peran Konservasi Keanekaragaman Hayati Dalam Menunjang Pembangunan Yang Berkelanjutan. Pros Semin Nas Penelitian, Pendidik dan Penerapan MIPA Fak MIPA, Univ Negeri Yogyakarta, 16 Mei 2009 2009;199–205.
Nations U. Goal 15 : Life on Land. Sustain. Dev. Goals2020;(d):167–96.
Elfahmi, Woerdenbag HJ, Kayser O. Jamu: Indonesian traditional herbal medicine towards rational phytopharmacological use. J Herb Med 2014;4(2):51–73.
Kuswantoro F. Mengenal Jeringau (Acorus calamus L.)Tumbuhan Akuatik Dengan Berbagai Manfaat Obat dan Budaya. Lemb. Ilmu Pengetah. Indones.2016;
Divya G, Gajalakshmi S, Mythili S, Sathiavelu* A. Pharmacological Activities of Acorus calamus: A Review. Asian J Biochem Pharm Res 2011;1(4).
Balakumbahan R, Rajamani K, Kumanan K. Acorus calamus: An overview. J. Med. Plants Res.2010;4(25).
Imam H, Riaz Z, Azhar M, Sofi G, Hussain A. Sweet flag (Acorus calamus Linn.): An incredible medicinal herb. Int. J. Green Pharm.2013;7(4).
Jadid N, Kurniawan E, Himayani CES, Andriyani, Prasetyowati I, Purwani KI, et al. An ethnobotanical study of medicinal plants used by the Tengger tribe in Ngadisari village, Indonesia. PLoS One 2020;15(7 July):1–16.
Rajput SB, Tonge MB, Karuppayil SM. An overview on traditional uses and pharmacological profile of Acorus calamus Linn. (Sweet flag) and other Acorus species. Phytomedicine 2014;21(3):268–76.
Silalahi M, Nisyawati, Walujo EB, Supriatna J, Mangunwardoyo W. The local knowledge of medicinal plants trader and diversity of medicinal plants in the Kabanjahe traditional market, North Sumatra, Indonesia. J Ethnopharmacol 2015;175:432–43.
¬¬Silalahi M, Khairiah A, Nisyawati. Ethnomedicinal plants and practices related to pregnancy, childbirth, and postpartum healthcare of minangkabau ethnic group, West Sumatra, Indonesia. Biodiversitas 2020;21(10):4597–605.
Silalahi M. Senyawa Bioaktif Pada Acorus Calamus (L.) Dan Pemanfaatannya Sebagai Obat Kanker Dan Antimikroba. J Din Pendidik 2018;11(1):95.
María R, Shirley M, Xavier C, Jaime S, David V, Rosa S, et al. Preliminary phytochemical screening, total phenolic content and antibacterial activity of thirteen native species from Guayas province Ecuador. J King Saud Univ - Sci 2018;30(4).
Gospel Ajuru M. Qualitative and Quantitative Phytochemical Screening of Some Plants Used in Ethnomedicine in the Niger Delta Region of Nigeria. J Food Nutr Sci 2017;5(5).
Tyagi T, Agarwal M. Phytochemical screening and GC-MS analysis of bioactive constituents in the ethanolic extract of Pistia stratiotes L. and Eichhornia crassipes (Mart.) solms. ~ 195 ~ J Pharmacogn Phytochem 2017;6(1).
Indrayani L, Soetjipto H, Sihasale L. SKRINING FITOKIMIA DAN UJI TOKSISITAS EKSTRAK DAUN PECUT KUDA (Stachytarpheta jamaicensis L. Vahl) TERHADAP LARVA UDANG Artemia salina Leach. Berk Penelit Hayati 2006;12(1).
Ilyasov I, Beloborodov V, Antonov D, Dubrovskaya A, Terekhov R, Zhevlakova A, et al. Flavonoids with glutathione antioxidant synergy: Influence of free radicals inflow. Antioxidants 2020;9(8).
Malik A, Edward F, Waris R. Skrining Fitokimia dan Penetapan Kandungan Flavonoid Total Ekstrak Metanolik Herba Boroco (Celosia argentea L). J Fitofarmaka Indones 2014;1(1):1–5.
Muchtaromah B, Ahmad M, S EK, A YM, A VL. Phytochemicals, Antioxidant and Antifungal Properties of Acorus calamus, Curcuma mangga, and Allium sativum. KnE Life Sci 2017;3(6).
Arifin B, Ibrahim S. STRUKTUR, BIOAKTIVITAS DAN ANTIOKSIDAN FLAVONOID. J Zarah 2018;6(1).
Pourmorad F, Hosseinimehr SJ, Shahabimajd N. Antioxidant activity, phenol and flavonoid contents of some selected Iranian medicinal plants. African J Biotechnol 2006;5(11).
Robinson T. Kandungan Organik Tumbuhan Tinggi. Diterjemahkan oleh Kosasih Padmawinata. 1995.
Ikalinus R, Widyastuti S, Eka Setiasih N. Skrining Fitokimia Ekstrak Etanol Kulit Batang Kelor (Moringa Oleifera). Indones Med Veterinus 2015;4(1).
Wang T yang, Li Q, Bi K shun. Bioactive flavonoids in medicinal plants: Structure, activity and biological fate. Asian J. Pharm. Sci.2018;13(1).
Shehzad A, Anwar MN, Zahid H, Ravinayagam V, Al-Rumaih HS, Al-Khulaifi F, et al. Multifactorial role of flavonoids in prevention and treatment of various cancers. An. la Real Acad. Nac. Farm.2016;82(3).
García-Lafuente A, Guillamón E. Anti-inflammatory properties of dietary flavonoids. In: Handbook on Flavonoids: Dietary Sources, Properties and Health Benefits. 2012.
Aniagu SO, Binda LG, Nwinyi FC, Orisadipe A, Amos S, Wambebe C, et al. Anti-diarrhoeal and ulcer-protective effects of the aqueous root extract of Guiera senegalensis in rodents. J Ethnopharmacol 2005;97(3).
Ashour AS, El Aziz MMA, Gomha Melad AS. A review on saponins from medicinal plants: chemistry, isolation, and determination. J Nanomedicine Res 2019;7(4).
Fahrunnida, Pratiwi R. Kandungan Saponin Buah, Daun dan Tangkai Daun Belimbing Wuluh (Averrhoa bilimbi L.). FKIP UNS 2015;
Francis G, Kerem Z, Makkar HPS, Becker K. The biological action of saponins in animal systems: a review. Br J Nutr 2002;88(6).
Soetan KO, Oyekunle MA, Aiyelaagbe OO, Fafunso MA. Evaluation of the antimicrobial activity of saponins extract of Sorghum Bicolor L. Moench. African J Biotechnol 2006;5(23).
Audina M, Yuliet, Khaerati K. Efektivitas AntiinflamasiI Ekstrak Etanol Daun Sumambu ( Hyptis capitata Jacq .) pada Tikus Jantan ( Rattus norvegicus L .). Bocelebes. Biocebeles 2018;12(2).
J.B Harbone. Metode Fitokimia: Penuntun Cara Modern Menganalisis Tumbuhan, diterjemahkan oleh Kosasih Padmawinata dan Iwang Soediro. Penerbit ITB, Bandung 1996;2.
Hasanah F. Skrining Fitokimia Dan Formulasi Sediaan Masker Peel-Off Ekstrak Etanol Gambir (Uncaria Gambir (W. Hunter) Roxb) Secara Perkolasi. BIOLINK J Biol Lingkung Ind Kesehat 2019;5(2).
Gómez-Cordovés C, Bartolomé B, Vieira W, Virador VM. Effects of wine phenolics and sorghum tannins on tyrosinase activity and growth of melanoma cells. J Agric Food Chem 2001;49(3).
Ballard CR, Maróstica MR. Health Benefits of Flavonoids. In: Bioactive Compounds: Health Benefits and Potential Applications. 2018.
Chowdhury S, Poddar SK, Zaheen S, Noor FA, Ahmed N, Haque S, et al. Phytochemical screening and evaluation of cytotoxic and hypoglycemic properties of Mangifera indica peels. Asian Pac J Trop Biomed 2017;7(1).
Bailly C, Vergoten G. Esculentosides: Insights into the potential health benefits, mechanisms of action and molecular targets. Phytomedicine2020;79.
Abu Zarin M, Wan HY, Isha A, Armania N. Antioxidant, antimicrobial and cytotoxic potential of condensed tannins from Leucaena leucocephala hybrid-Rendang. Food Sci Hum Wellness 2016;5(2).
Jain D, Gupta S, Jain R, Jain N. Anti-inflammatory Activity of 80% Ethanolic Extract of Acorus calamus Linn. Leaves in Albino Rats. Res J Pharm Technol 2010;3(3).
Palani S, Raja S, Kumar RP, Parameswaran P, Kumar BS. Therapeutic efficacy of Acorus calamus on acetaminophen induced nephrotoxicity and oxidative stress in male albino rats. Acta Pharm Sci 2010;52(1).
Khurana N, Jain PK, Pounikar Y, Sharma N. Pharmacological evaluation of rhizomes of acorus calamus for analgesic activity. Int J Pharm Pharm Sci 2015;7(4).
Jayaraman R, Anitha T, Joshi VD. Analgesic and anticonvulsant effects of Acorus calamus roots in mice. Int J PharmTech Res 2010;2(1).
Phongpaichit S, Pujenjob N, Rukachaisirikul V, Ongsakul M. Antimicrobial activities of the crude methanol extractof Acorus calamus Linn. Songklanakarin J Sci Technol 2005;27.
